diff --git a/httpcore5/src/main/java/org/apache/hc/core5/reactor/SingleCoreIOReactor.java b/httpcore5/src/main/java/org/apache/hc/core5/reactor/SingleCoreIOReactor.java
index e5839b3e8..462f0e0df 100644
--- a/httpcore5/src/main/java/org/apache/hc/core5/reactor/SingleCoreIOReactor.java
+++ b/httpcore5/src/main/java/org/apache/hc/core5/reactor/SingleCoreIOReactor.java
@@ -37,6 +37,7 @@
 import java.net.UnknownHostException;
 import java.nio.channels.CancelledKeyException;
 import java.nio.channels.ClosedChannelException;
+import java.nio.channels.ClosedSelectorException;
 import java.nio.channels.SelectionKey;
 import java.nio.channels.SocketChannel;
 import java.util.Queue;
@@ -434,7 +435,13 @@ private void processConnectionRequest(final SocketChannel socketChannel, final I
     }
 
     private void closeOpenChannels() {
-        for (final SelectionKey key : selector.keys()) {
+        final Set<SelectionKey> keys;
+        try {
+            keys = selector.keys();
+        } catch (final ClosedSelectorException ignore) {
+            return;
+        }
+        for (final SelectionKey key : keys) {
             final Object attachment = key.attachment();
             if (attachment instanceof InternalChannel) {
                 final InternalChannel channel = (InternalChannel) attachment;
diff --git a/httpcore5/src/test/java/org/apache/hc/core5/reactor/TestSingleCoreIOReactor.java b/httpcore5/src/test/java/org/apache/hc/core5/reactor/TestSingleCoreIOReactor.java
index 4723f93c6..8b2e2ad97 100644
--- a/httpcore5/src/test/java/org/apache/hc/core5/reactor/TestSingleCoreIOReactor.java
+++ b/httpcore5/src/test/java/org/apache/hc/core5/reactor/TestSingleCoreIOReactor.java
@@ -26,10 +26,17 @@
  */
 package org.apache.hc.core5.reactor;
 
+import java.net.InetAddress;
 import java.net.InetSocketAddress;
+import java.nio.channels.ServerSocketChannel;
 import java.nio.channels.SocketChannel;
+import java.util.List;
+import java.util.concurrent.CopyOnWriteArrayList;
+import java.util.concurrent.CountDownLatch;
+import java.util.concurrent.TimeUnit;
 
 import org.apache.hc.core5.function.Decorator;
+import org.apache.hc.core5.io.CloseMode;
 import org.apache.hc.core5.net.NamedEndpoint;
 import org.apache.hc.core5.util.Timeout;
 import org.junit.jupiter.api.Assertions;
@@ -91,4 +98,37 @@ void enqueueAfterShutdownThrows() throws Exception {
         }
     }
 
+    @Test
+    void terminatesWhenSelectorClosedByAnotherThread() throws Exception {
+        final CountDownLatch connected = new CountDownLatch(1);
+        final CountDownLatch reactorClosed = new CountDownLatch(1);
+        final IOEventHandler handler = Mockito.mock(IOEventHandler.class);
+        Mockito.doAnswer(invocation -> {
+            connected.countDown();
+            reactorClosed.await();
+            return null;
+        }).when(handler).connected(Mockito.any());
+        final List<Exception> exceptions = new CopyOnWriteArrayList<>();
+        try (ServerSocketChannel server = ServerSocketChannel.open()) {
+            server.bind(new InetSocketAddress(InetAddress.getLoopbackAddress(), 0));
+            try (SocketChannel client = SocketChannel.open(server.getLocalAddress());
+                 SocketChannel channel = server.accept()) {
+                final SingleCoreIOReactor reactor = new SingleCoreIOReactor(
+                        exceptions::add, (session, attachment) -> handler, IOReactorConfig.DEFAULT, null, null, null, null);
+                final Thread worker = new Thread(reactor::execute);
+                worker.start();
+                reactor.enqueueChannel(new ChannelEntry(channel, null));
+                Assertions.assertTrue(connected.await(5, TimeUnit.SECONDS));
+
+                reactor.close(CloseMode.IMMEDIATE);
+                reactorClosed.countDown();
+                worker.join(TimeUnit.SECONDS.toMillis(5));
+
+                Assertions.assertFalse(worker.isAlive());
+                Assertions.assertTrue(exceptions.isEmpty(), exceptions::toString);
+                Mockito.verify(handler).disconnected(Mockito.any());
+            }
+        }
+    }
+
 }